Drug Sensing and Delivery
Beschrijving
The growth of new diagnostic methods and advances in information technology has led to the recent rise of precision and personalized medicine. Essential for successful personalized medicine is getting an optimal concentration of a drug at the precise location of action and knowing what should be measured to attain the best possible effect.
Students acquire in depth knowledge in pharmacokinetics and -dynamics, drug delivery systems and controlled drug release. Students learn established and novel techniques to determine patient specific characteristics (e.g. genomics and metabolomics). Students use these characteristics to predict an individual's response and tailor the treatment.
Topics:
- Pharmacokinetics
- Pharmacodynamics
- Drug delivery systems
- Controlled-drug-release
- Active implantable medical devices
- Closed loop systems (feedback control)
- Biomarkers / metabolomics
- DNA analysis / genomics
- Fluid dynamics (minimizing sample size)
- Follow-up and compliance
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