Algorithms for Sequence-based Bioinformatics

After having followed this course, the student has a good understanding of algorithms and data structures in genomics used for DNA sequence analysis. The student is able to implement algorithms in python, and can translate methods described in scientific literature into a working implementation.

Bioinformatics analyses in genomics aim to compare large sets of genomes in order to understand and explain differences in traits of an organism. Contemporary methods are powered by fundamental algorithms and data structures, which are efficient and scale to large data sets. A thorough understanding of these algorithms and data structures is necessary for advanced users and developers in this area.

Bioinformatics application domains that are covered include: variant calling, motif detection, genome assembly, sequence alignment, DNA sequencing.